Natural scienceBioinformaticsDNA sequencingIllumina

Limitations and errors of the Illumina method

Adapting to the adapters

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Is it possible to resolve the read through adapters problem?

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Well, technically yes, but you have to rerun the experiment..

No, you're doomed

Yes, you can simply detect adapter sequences and trim them

Yes, you can detect adapter sequences and "subtract" them during alignment

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