Natural scienceBioinformaticsBioinformatics algorithmsAlignment algorithms

Multiple alignment

Exhaustive vs heuristic algorithms

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Why progressive alignment of multiple sequences is faster than multidimensional dynamic programming?

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Progressive method doesn't examine all possible multiple alignments

Progressive method doesn't include building all pairwise alignments

Progressive alignment algorithms don't perform 2-dimensional dynamic programming at any step

Progressive alignment is a heuristic, and doesn't guarantee an optimal solution

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