Natural scienceBioinformaticsBioinformatics algorithmsAlignment algorithms

Introduction to BLAST

Talking about significance

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What is the correct definition of E-value? All definitions imply a database of the same size and the same length of input sequence.

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E-value is an expected number of hits with higher scores than we observed in the alignment

E-value is an expected number of hits with such as good scores as in observed alignment or better

E-value is a probability of having such as good scores as in observed alignment or better

E-value is an expected number of hits with same scores as in observed alignment or with lower scores

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